Northampton Town sacked Aidy Boothroyd after losing against Wycombe Wanderers, while Oxford United failed to reclaim top spot on Saturday.
Northampton dropped to the bottom of League Two after the 4-1 home defeat and Torquay United s 1-0 win over Dagenham and Redbridge.
Jo Kuffour and Kortney Hause scored in the first 14 minutes for Wycombe, and although Izale McLeod pulled a goal back just after half-time, Wycombe responded strongly to finish with a flurry.
Stuart Lewis and Dean Morgan netted late goals as Wycombe sealed their first league success in more than two months – prompting Northampton to act and dismiss manager Boothroyd.
A short statement on the club s official website read: Aidy Boothroyd has left Northampton Town Football Club.
The decision was made by chairman David Cardoza after Saturday s loss to Wycombe Wanderers.
The club will make no further comment at this time, but will provide a further update on Monday.
Oxford missed the chance to move ahead of leaders Chesterfield after being held to a frustrating 0-0 draw at York City. York have not won a match since October.
Scunthorpe United s surge up the table continued as they extended their unbeaten run to five matches, of which four have been wins, with a 2-0 home success against Morecambe.
Deon Burton scored both goals for Scunthorpe, who are third in the table.
Fourth-placed Fleetwood Town were upset 2-0 at home by Cheltenham Town, with Troy Brown and Jermaine McGlashan getting on the scoresheet for the victors.
Bury are in the relegation zone after losing 2-1 at Plymouth Argyle – Reuben Reid struck the winner with 12 minutes to play.
Portsmouth s collapse continued, as their winless run extended to nine matches, of which seven have been defeats.
The 2008 FA Cup winners were beaten 2-0 at Bristol Rovers, who scored through Ollie Clarke and David Clarkson.
And Mansfield Town s wretched record also grew older – Accrington Stanley beat them 3-2 in a thrilling encounter.
Accrington Stanley trailed 2-1 in the fourth minute of stoppage time, but late goals from Kal Naismith and James Gray sealed an incredible win for James Beattie s side.
Mansfield have not won a league match since September.
Other results on Saturday saw Burton Albion s unbeaten run stretch to seven matches, as they drew 1-1 at Hartlepool United, while Aaron Downes strike was enough for Torquay.
And Newport County s match with AFC Wimbledon was postponed after a pitch inspection at Rodney Parade.
